Antitumor Fungal Metabolites
نویسندگان
چکیده
Several biologically active keto-epoxides, containing a unique decalone with a spiro-ketal linkage through a naphthalene moiety, have been isolated from various fungi.1 ~ 7) In the course of our continuing search for new antitumor agents, two novel minor metabolites, Sch 50673 (1) and Sch 50676 (2) were discovered from the fungus, Nattrassia mangiferae (ATCC74078), in a large scale fermentation broth. This paper describes the fermentation, isolation, structure elucidation and bio-
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تاریخ انتشار 2006